Cryosurgery for hepatocellular carcinoma

Hepatocellular Carcinoma in Sheep

Preclinical studies of 166Ho-chitosan for treatment of hepatocellular carcinoma

Introduction: Recently, due to the special characteristics of 166Ho and chitosan, 166Ho-chitosan complex was developed for treatment of tumors such as hepatocellular carcinoma. This complex has been lately prepared with high radiochemical purity in our lab. The preclinical studies of the complex however should be performed to evaluate the tracer concentration in target and...

Hepatocellular carcinoma in a sheep

At necropsy of a five-year-old sheep, a pear shaped, lobular yellow-brownish mass measuring about 12 ×15 × 20 cm was found to involve the right hepatic lobe. Microscopic examination revealed two trabecularand solid patterns of neoplastic hepatocytes. In solid pattern, there were numerous tumoral giant cells thatcontain one or more large hyperchromatic bizarre-shaped nuclei scattered among clust...

Comparison of percutaneous cryosurgery and surgical resection for the treatment of small hepatocellular carcinoma

The present study aimed to compare the outcome of percutaneous cryosurgery (PC) with surgical resection (SR) in the treatment of solitary, small hepatocellular carcinoma (HCC), by performing a retrospective cohort study on 82 patients with solitary HCCs who had received either PC (24 patients) or SR (58 patients). All patients underwent pretreatment blood chemistry tests and an imaging evaluati...

Cryosurgery in the treatment of rectal carcinoma.

All patients came to cryosurgery with the histological diagnosis of well-differentiated adenocarcinoma established (Table 1). Two were unfit for surgery on medical grounds, while the other two refused operative treatment (Table 2). The tumours were frozen using a cryoprobe cooled by nitrous oxide (KRYMED MT 600, the probe tip being a T2500 maxiderm). The machine produced and maintained temperat...